Box Warning

GLP-1 receptor agonists (such as Semaglutide and Tirzepatide) carry a boxed warning regarding a potential risk of thyroid C-cell tumors. These medications are not recommended for individuals with:

• A personal or family history of medullary thyroid carcinoma (MTC)
• A diagnosis of multiple endocrine neoplasia syndrome type 2 (MEN-2)

General Warnings

• Kidney function: Vomiting, nausea, or diarrhea can lead to dehydration; drink adequate water and contact your provider if symptoms persist.
• Gastrointestinal effects: Slowed stomach emptying can cause bloating, nausea, or feeling full early during meals. Eat slowly and stop when satisfied.
• Pancreatitis: Seek immediate care for severe upper-abdominal pain radiating to the back, with or without vomiting.
• Gallbladder health: Rapid weight loss can increase gallstone risk; notify your provider if you experience upper-right abdominal pain.

Common Side Effects

Most side effects are mild and temporary, improving as your body adjusts to treatment. These may include:

• Mild nausea, bloating, or decreased appetite
• Occasional constipation or loose stools
• Fatigue or mild headache during dose escalation
• Injection-site tenderness (typically resolves within hours)

Drug Interactions

Always inform your provider about all medications, supplements, and over-the-counter products you are using. GLP-1 and GIP medications may delay stomach emptying, which can affect how oral medications are absorbed. Your provider will help determine if timing adjustments are necessary.

When to Contact Your Provider

• Severe or persistent nausea, vomiting, or dehydration
• Severe abdominal pain, especially with fever or jaundice
• Sudden swelling of the neck or difficulty swallowing
• Shortness of breath or new chest pain

Educational Notice

VeyraRx™ therapies are prescribed under licensed provider supervision and compounded through U.S.-based 503A/503B pharmacies. The information above is provided for educational purposes and is not a substitute for medical care. Always follow your provider’s guidance and pharmacy instructions.